Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | DRD4 | P21917 | 6/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 6/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468710 | 0.95 | CACNA1G (0.43) | CACNA1GKCNH2MCHR1DRD3DRD4 | |
| SCHEMBL7463847 | 0.93 | DRD3 (0.48) | CACNA1GKCNH2MCHR1DRD3DRD4 | |
| SCHEMBL7455892 | 0.92 | MCHR1 (0.43) | MCHR1DRD3DRD2PYGL | |
| SCHEMBL7461458 | 0.89 | MCHR1 (0.53) | MCHR1DRD3DRD2PYGL | |
| SCHEMBL7470930 | 0.88 | MCHR1 (0.42) | MCHR1DRD3PYGL | |
| SCHEMBL7460453 | 0.88 | CCR1 (0.44) | MCHR1DRD3DRD2PYGL | |
| SCHEMBL7458988 | 0.88 | MCHR1 (0.48) | MCHR1DRD3PYGL | |
| SCHEMBL7466978 | 0.88 | KDM4E (0.46) | MCHR1DRD3DRD4DRD2ACHE | |
| SCHEMBL7465486 | 0.87 | DRD4 (0.48) | CACNA1GKCNH2MCHR1DRD3DRD4 | |
| SCHEMBL7467819 | 0.85 | MCHR1 (0.53) | MCHR1DRD3DRD2PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |