Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460453 | 0.91 | CCR1 (0.44) | DRD2DRD3MCHR1CCR1CCR3 | |
| SCHEMBL7463222 | 0.91 | MCHR1 (0.53) | KDM4EDRD2DRD3MAPTALDH1A1 | |
| SCHEMBL7466835 | 0.91 | MCHR1 (0.45) | KDM4EDRD2DRD3ALDH1A1MCHR1 | |
| SCHEMBL7470930 | 0.90 | MCHR1 (0.42) | DRD3MCHR1 | |
| SCHEMBL7455892 | 0.90 | MCHR1 (0.43) | DRD2DRD3MCHR1CCR1CCR3 | |
| SCHEMBL7458988 | 0.90 | MCHR1 (0.48) | DRD3MCHR1CCR1CCR3 | |
| SCHEMBL7460484 | 0.88 | CACNA1G (0.43) | DRD2DRD3MCHR1DRD4ACHE | |
| SCHEMBL7459200 | 0.85 | MCHR1 (0.45) | KDM4EDRD2DRD3ALDH1A1MCHR1 | |
| SCHEMBL7468710 | 0.85 | CACNA1G (0.43) | DRD2DRD3MCHR1DRD4ACHE | |
| SCHEMBL7465649 | 0.85 | MCHR1 (0.46) | KDM4EDRD2DRD3ALDH1A1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |