Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7407711 | 0.99 | HTR2A (0.43) | HTR2ACHRM2CHRM1CHRM3DRD2 | |
| SCHEMBL7410402 | 0.83 | CHRM3 (0.59) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| SCHEMBL11347383 | 0.83 | CHRM2 (0.43) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7410820 | 0.82 | CHRM2 (0.42) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7409289 | 0.79 | HTR1F (0.41) | CHRM2CHRM1CHRM3MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11426753 | 0.79 | HTR1F (0.44) | CHRM2CHRM1CHRM3HTR1ASLC6A2 | |
| SCHEMBL7143900 | 0.77 | ADRA1A (0.49) | SLC6A4MAOAMAOBHTR1F | |
| SCHEMBL7410439 | 0.77 | CTSV (0.46) | TDP1MAOAMAOBHTR1F | |
| Hydrochloric Acid SCHEMBL7413220 | 0.77 | EGFR (0.50) | MAOAMAOBHTR1F | |
| Hydrochloric Acid SCHEMBL7406728 | 0.77 | CTSV (0.46) | MAOAMAOBHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |