Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458898 | 0.89 | BRD9 (0.36) | GRM8CYP1A2CYP2C9TACR1GRM7 | |
| SCHEMBL7460285 | 0.86 | TNF (0.35) | GRM8CYP1A2CYP2C9TACR1GRM7 | |
| SCHEMBL7460643 | 0.86 | PTGS2 (0.35) | CYP1A2CYP2C9BRD9 | |
| SCHEMBL7461244 | 0.83 | MEN1 (0.31) | CTSA | |
| SCHEMBL7462939 | 0.83 | USP7 (0.33) | BRD9CTSA | |
| SCHEMBL7453725 | 0.83 | — | — | |
| SCHEMBL7453450 | 0.81 | BRD9 (0.34) | GRM8CYP1A2CYP2C9TACR1GRM7 | |
| SCHEMBL7459099 | 0.81 | BRD9 (0.36) | CYP2C9BRD9 | |
| SCHEMBL7462374 | 0.81 | BCAT1 (0.42) | CYP2C9 | |
| SCHEMBL7458110 | 0.80 | PABPC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |