SCHEMBL7460822

SCHEMBL7460822

[c]1cc2c(-c3ccccc3)cccc2o1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
RAB9A P51151 2/20 0.37
KDM4E B2RXH2 2/20 0.37
METAP2 P50579 1/20 0.37
TNF P01375 1/20 0.37
MAOB P27338 1/20 0.37
DPP4 P27487 1/20 0.35
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
HSD17B10 Q99714 3/20 0.34
HPGD P15428 2/20 0.34
MAPK1 P28482 2/20 0.34
BCL2L1 Q07817 1/20 0.34
CYP2A6 P11509 1/20 0.34
MAP4K4 O95819 1/20 0.33
CSF1R P07333 1/20 0.33
FGFR1 P11362 1/20 0.33
PDGFRA P16234 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295801 0.84 PIK3CD (0.44) ALDH1A1RAB9AKDM4ETNFKMT2A
SCHEMBL21296073 0.80 CYP11B1 (0.44) ALDH1A1RAB9AKDM4ETNFMAOB
SCHEMBL21295644 0.74 KDM4E (0.42) ALDH1A1RAB9AKDM4EMETAP2HSD17B10
SCHEMBL2391683 0.71 ALDH1A1 (0.52) ALDH1A1RAB9AKDM4EMETAP2TNF
SCHEMBL513256 0.69 HPGD (0.38) ALDH1A1RAB9AKDM4EKMT2AMEN1
SCHEMBL513244 0.69
SCHEMBL21296179 0.69 ADORA3 (0.40) ALDH1A1RAB9AKDM4ETNFMAOB
SCHEMBL2143620 0.68 MAOB (0.45) ALDH1A1RAB9AKDM4EMETAP2TNF
SCHEMBL30080985 0.67 METAP2 (0.48) ALDH1A1KDM4EMETAP2TNFDPP4
SCHEMBL28322994 0.67 METAP2 (0.48) ALDH1A1KDM4EMETAP2TNFDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed
EP-1244617-A1 SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE Ortho-McNeil Pharmaceutical, Inc. (US) 2002-10-02 EP disclosed
WO-2001047875-A1 SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-07-05 WO disclosed