Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468826 | 0.92 | EGFR (0.56) | EGFRHTR6MAPTALDH1A1TDP1 | |
| SCHEMBL7470206 | 0.89 | EGFR (0.52) | EGFRHTR6MAPTALDH1A1TDP1 | |
| SCHEMBL7459198 | 0.88 | MEN1 (0.53) | EGFRTLR7ALDH1A1KDM4ELMNA | |
| SCHEMBL7458928 | 0.87 | EGFR (0.47) | EGFRHTR6MAPTALDH1A1TDP1 | |
| SCHEMBL7475684 | 0.86 | EGFR (0.53) | EGFRHTR6MAPTALDH1A1TDP1 | |
| SCHEMBL7468699 | 0.85 | PDE5A (0.44) | EGFRHTR6MAPTALDH1A1LMNA | |
| SCHEMBL7463091 | 0.85 | USP10 (0.50) | EGFRHTR6MAPTALDH1A1LMNA | |
| SCHEMBL7465445 | 0.85 | HTR6 (0.55) | EGFRHTR6HTT | |
| SCHEMBL7466331 | 0.85 | ALDH1A1 (0.48) | EGFRHTR6MAPTALDH1A1KDM4E | |
| SCHEMBL7463395 | 0.84 | HTT (0.55) | EGFRMAPTALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |