Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475684 | 0.92 | EGFR (0.53) | ALDH1A1HTTEGFRHTR6LMNA | |
| SCHEMBL7464149 | 0.91 | HTR6 (0.44) | ALDH1A1HTTHTR6LMNAMAPT | |
| SCHEMBL7463091 | 0.91 | USP10 (0.50) | ALDH1A1HTTEGFRHTR6LMNA | |
| SCHEMBL7465445 | 0.91 | HTR6 (0.55) | HTTEGFRHTR6TP53KMT2A | |
| SCHEMBL7458928 | 0.91 | EGFR (0.47) | ALDH1A1HTTEGFRHTR6LMNA | |
| SCHEMBL7468826 | 0.91 | EGFR (0.56) | ALDH1A1HTTKDM4EEGFRHTR6 | |
| SCHEMBL7459198 | 0.90 | MEN1 (0.53) | ALDH1A1HTTKDM4ENPC1EGFR | |
| SCHEMBL7468699 | 0.89 | PDE5A (0.44) | ALDH1A1EGFRHTR6LMNAMAPT | |
| SCHEMBL7525155 | 0.88 | EGFR (0.48) | EGFRHTR6LMNAMAPTKMT2A | |
| SCHEMBL7536681 | 0.88 | TDP1 (0.46) | EGFRHTR6LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |