Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475684 | 0.90 | EGFR (0.53) | EGFRHTR6ALDH1A1LMNAGAA | |
| SCHEMBL7458928 | 0.89 | EGFR (0.47) | EGFRHTR6ALDH1A1LMNAGAA | |
| SCHEMBL7465445 | 0.89 | HTR6 (0.55) | EGFRHTR6TP53MAPK1WDR5 | |
| SCHEMBL7463091 | 0.89 | USP10 (0.50) | EGFRHTR6ALDH1A1LMNATP53 | |
| SCHEMBL7466331 | 0.89 | ALDH1A1 (0.48) | PDE5AEGFRHTR6ALDH1A1LMNA | |
| SCHEMBL7468826 | 0.89 | EGFR (0.56) | EGFRHTR6ALDH1A1LMNATSHR | |
| SCHEMBL7525155 | 0.87 | EGFR (0.48) | EGFRHTR6LMNAMAPTKMT2A | |
| SCHEMBL7459198 | 0.87 | MEN1 (0.53) | PDE5AEGFRALDH1A1LMNAMAPK1 | |
| SCHEMBL7473662 | 0.86 | USP10 (0.47) | EGFRHTR6ALDH1A1LMNAGAA | |
| SCHEMBL7465224 | 0.86 | MAPT (0.44) | EGFRHTR6ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |