Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460969 | 0.88 | ACHE (0.41) | HTR6HPGDSMN1; SMN2WDR5KMT2A | |
| SCHEMBL7458939 | 0.84 | SMN1; SMN2 (0.44) | HTR6HPGDSMN1; SMN2WDR5KMT2A | |
| SCHEMBL7475690 | 0.84 | SMN1; SMN2 (0.44) | HTR6HPGDSMN1; SMN2WDR5KMT2A | |
| SCHEMBL7463550 | 0.82 | ACHE (0.40) | HTR6HPGDSMN1; SMN2WDR5KMT2A | |
| SCHEMBL7459092 | 0.82 | HTR6 (0.42) | HTR6HPGDSMN1; SMN2WDR5KMT2A | |
| SCHEMBL7475452 | 0.82 | EGFR (0.52) | ABCG2EGFRPDGFRB | |
| SCHEMBL7468826 | 0.82 | EGFR (0.56) | HTR6HPGDSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7468704 | 0.81 | SMN1; SMN2 (0.42) | HTR6HPGDSMN1; SMN2WDR5KMT2A | |
| SCHEMBL7469187 | 0.81 | HPGD (0.40) | HTR6HPGDSMN1; SMN2WDR5KMT2A | |
| SCHEMBL7460925 | 0.80 | EGFR (0.48) | HTR6HPGDHTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |