Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466558 | 0.85 | EGFR (0.46) | ACHEBACE1CNR1ABCG2EGFR | |
| SCHEMBL7460969 | 0.83 | ACHE (0.41) | ACHEBACE1HPGDSMN1; SMN2ABCG2 | |
| SCHEMBL7460928 | 0.82 | HTR6 (0.41) | ACHEBACE1HPGDSMN1; SMN2ABCG2 | |
| SCHEMBL7458939 | 0.81 | SMN1; SMN2 (0.44) | ACHEBACE1HPGDSMN1; SMN2ABCG2 | |
| SCHEMBL7475690 | 0.81 | SMN1; SMN2 (0.44) | ACHEBACE1HPGDSMN1; SMN2ABCG2 | |
| SCHEMBL7459092 | 0.79 | HTR6 (0.42) | ACHEBACE1HPGDSMN1; SMN2ABCG2 | |
| SCHEMBL7536684 | 0.79 | SMN1; SMN2 (0.42) | ACHEBACE1HPGDSMN1; SMN2ABCG2 | |
| SCHEMBL7468704 | 0.78 | SMN1; SMN2 (0.42) | ACHEBACE1HPGDSMN1; SMN2ABCG2 | |
| SCHEMBL7472430 | 0.78 | SMN1; SMN2 (0.39) | ACHEBACE1HPGDSMN1; SMN2EGFR | |
| SCHEMBL7469187 | 0.78 | HPGD (0.40) | ACHEBACE1HPGDSMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |