Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463599 | 0.96 | L3MBTL1 (0.36) | L3MBTL1TDP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL7458051 | 0.94 | L3MBTL1 (0.35) | L3MBTL1PTGER1TP53KDM4EALDH1A1 | |
| SCHEMBL7462120 | 0.94 | HTR6 (0.34) | L3MBTL1PTGDR2 | |
| SCHEMBL7464601 | 0.93 | PTGER1 (0.33) | L3MBTL1PTGER1PTGDR2 | |
| SCHEMBL7468910 | 0.93 | PTGER3 (0.35) | L3MBTL1PTGER1RAPGEF3PTGER3ALDH1A1 | |
| SCHEMBL7462639 | 0.93 | EGFR (0.34) | L3MBTL1TDP1TP53RAPGEF3PTGER3 | |
| SCHEMBL7461635 | 0.92 | RAPGEF3 (0.35) | L3MBTL1TDP1TP53RAPGEF3KDM4E | |
| SCHEMBL7463725 | 0.92 | KMT2A (0.42) | L3MBTL1GAA | |
| SCHEMBL7460136 | 0.91 | MEN1 (0.33) | TP53 | |
| SCHEMBL7460235 | 0.91 | PTGER3 (0.34) | TP53RAPGEF3PTGER3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |