Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.66 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457737 | 0.91 | MCHR1 (0.63) | MCHR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7466687 | 0.88 | MCHR1 (0.59) | MCHR1CHRM4 | |
| SCHEMBL7461314 | 0.86 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL7460992 | 0.85 | MCHR1 (0.60) | MCHR1 | |
| SCHEMBL7464540 | 0.84 | MCHR1 (0.59) | MCHR1 | |
| SCHEMBL7461973 | 0.84 | MCHR1 (0.58) | MCHR1 | |
| SCHEMBL7464781 | 0.82 | MCHR1 (0.73) | MCHR1 | |
| SCHEMBL7467049 | 0.80 | MCHR1 (0.73) | MCHR1S1PR1 | |
| SCHEMBL7470119 | 0.80 | MCHR1 (0.68) | MCHR1 | |
| SCHEMBL7470937 | 0.80 | MCHR1 (0.58) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |