Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 14/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460709 | 0.89 | MCHR1 (0.55) | HTR7MCHR1HTR2AHTR1ADRD2 | |
| SCHEMBL25758563 | 0.84 | HTR7 (0.69) | HTR7POLBHTR6HTR2AHTR1A | |
| SCHEMBL7461976 | 0.84 | BCHE (0.55) | HTR7MCHR1HTR6HTR2AHTR1A | |
| SCHEMBL25758471 | 0.82 | HTR7 (0.60) | HTR7POLBHTR6HTR2AHTR1A | |
| SCHEMBL7464678 | 0.81 | MCHR1 (0.49) | HTR7MCHR1POLBHTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL7454984 | 0.81 | MCHR1 (0.55) | HTR7MCHR1HTR2AHTR1ADRD2 | |
| SCHEMBL7460619 | 0.80 | MCHR1 (0.47) | HTR7MCHR1DRD2BCHEKMT2A | |
| Hydrochloric Acid SCHEMBL7459316 | 0.79 | BCHE (0.48) | HTR7MCHR1HTR6HTR2ADRD2 | |
| SCHEMBL7461241 | 0.78 | OPRM1 (0.55) | HTR7MCHR1HTR2AHTR1ABCHE | |
| SCHEMBL7470213 | 0.78 | HTR1A (0.57) | HTR7MCHR1POLBHTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0712845-B1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5633248-A | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS, DIARYLALKYLIDENEDIAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0712845-A1 | Amine compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |