Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459856 | 0.88 | S100B (0.35) | KMT2AMEN1MAPTLMNATP53 | |
| SCHEMBL7460447 | 0.82 | S100B (0.36) | KMT2AMEN1MAPTLMNATP53 | |
| SCHEMBL7812166 | 0.80 | KMT2A (0.32) | KMT2AMEN1MAPTLMNATP53 | |
| SCHEMBL7460055 | 0.80 | MAPT (0.34) | KMT2AMEN1MAPTLMNATP53 | |
| SCHEMBL7462051 | 0.79 | BCAT2 (0.33) | KMT2AMEN1MAPTLMNATP53 | |
| SCHEMBL7457018 | 0.79 | ALDH1A1 (0.32) | KMT2AMEN1MAPTLMNATP53 | |
| SCHEMBL6572913 | 0.76 | KMT2A (0.38) | KMT2AMEN1MAPTLMNATP53 | |
| SCHEMBL4614878 | 0.76 | CHEK2 (0.36) | KMT2AMEN1MAPTLMNATP53 | |
| SCHEMBL7800733 | 0.76 | CYP2A6 (0.40) | KMT2AMEN1MAPTLMNATP53 | |
| SCHEMBL7809878 | 0.76 | CYP2A6 (0.37) | KMT2AMEN1MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963982-B1 | New diaminobenzene derivatives and these componends containing colouring agents | WELLA AG (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-6132475-A | FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-10-17 | — | — | US | disclosed |
| EP-0963982-A2 | New diaminobenzene derivatives and these componends containing colouring agents | Wella Aktiengesellschaft (DE) | 1999-12-15 | — | — | EP | disclosed |