Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 3/20 | 0.43 |
| ▸ | EDNRB | P24530 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10514929 | 0.87 | LMNA (0.56) | LMNACYP1A2ALDH1A1TDP1TSHR | |
| SCHEMBL30748281 | 0.80 | IDO1 (0.56) | LMNACYP1A2ALDH1A1TDP1TSHR | |
| SCHEMBL6588863 | 0.80 | GPR35 (0.47) | LMNACYP1A2ALDH1A1TSHRCA9 | |
| SCHEMBL6593057 | 0.80 | LMNA (0.46) | LMNACYP1A2ALDH1A1TDP1CA9 | |
| SCHEMBL6962602 | 0.80 | IDO1 (0.56) | LMNACYP1A2ALDH1A1TDP1TSHR | |
| SCHEMBL29571343 | 0.76 | LMNA (0.52) | LMNACYP1A2ALDH1A1TDP1CA9 | |
| SCHEMBL19142316 | 0.76 | MEN1 (0.46) | LMNACYP1A2ALDH1A1CA9MEN1 | |
| SCHEMBL6833141 | 0.76 | LMNA (0.52) | LMNACYP1A2ALDH1A1TDP1CA9 | |
| SCHEMBL7247038 | 0.76 | HIF1A (0.47) | LMNACYP1A2ALDH1A1CA9MEN1 | |
| SCHEMBL28961641 | 0.75 | LMNA (0.51) | LMNACYP1A2ALDH1A1TSHRCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115976586-A | Positive and negative pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating | 昆山一鼎工业科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115976586-B | Forward and reverse pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating | 昆山一鼎工业科技有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-114437062-B | Compound capable of being used as sodium channel regulator and application thereof | 成都海博为药业有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-115976586-A | Positive and negative pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating | 昆山一鼎工业科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-114437062-A | Compound capable of being used as sodium channel regulator and application thereof | 成都海博为药业有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-3192792-B1 | AMINOSULFONYL-BASED COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | SUZHOU VIGONVITA LIFE SCIENCES CO LTD (CN) | 2022-03-09 | — | — | EP | disclosed |
| US-10093679-B2 | Amino sulfonyl-based compounds, the preparation method therefor and use thereof | SUZHOU VIGONVITA LIFE SCIENCES CO., LTD (CN) | 2018-10-09 | — | — | US | disclosed |
| US-20170298080-A1 | AMINOSULFONYL COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2017-10-19 | — | — | US | disclosed |
| EP-3004110-B1 | PYRAZOLOPYRROLIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2017-07-26 | — | — | EP | disclosed |
| EP-3192792-A1 | AMINOSULFONYL COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Suzhou Vigonvita Life Sciences Co., Ltd. (CN) | 2017-07-19 | — | — | EP | disclosed |
| US-20140349990-A1 | Pyrazolopyrrolidine Derivatives and their Use in the Treatment of Disease | NOVARTIS AG (CH) | 2014-11-27 | — | — | US | disclosed |
| US-7655688-B2 | Treating nuclear hormone receptor-associated conditions such as cancer and immune disorders; (3a alpha ,4 alpha ,7 alpha ,7a alpha )-2-(3-Chloro-4-hydroxyphenyl)hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655688-B2 | Treating nuclear hormone receptor-associated conditions such as cancer and immune disorders; (3a alpha ,4 alpha ,7 alpha ,7a alpha )-2-(3-Chloro-4-hydroxyphenyl)hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| US-6355796-B1 | REACTING BETA-AMINO-BETA-(PERFLUOROALKYL)ACRYLATE COMPOUND WITH BASE AND CARBAMOYL CHLORIDE COMPOUND TO FORM UREA COMPOUND, REACTING UREA COMPOUND WITH PHOSPHORUS PENTAHALIDE OR OXALYL HALIDE | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-12 | — | — | US | disclosed |
| EP-1169308-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 1,3-OXAZIN-6-ONES AND URACILS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-09 | — | — | EP | disclosed |
| US-6156700-A | 3-(1,2-Benzisothiazol- and isoxazol-5-yl)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-yl)-4(3H)-pyrimidinone or thione herbicidal agents | AMERICAN CYANMID COMPANY (US) | 2000-12-05 | — | — | US | disclosed |
| WO-2000049002-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 1,3-OXAZIN-6-ONES AND URACILS | AMERICAN CYANAMID COMPANY (US) | 2000-08-24 | — | — | WO | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1999014216-A1 | SUBSTITUTED 3(-1,2-BENZISOTHIAZOL OR ISOXAZOL-5 YL)-SUBSTITUTED PYRIMIDINE AS HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10093679-B2 | Amino sulfonyl-based compounds, the preparation method therefor and use thereof | SLC6A11, HADHB, NOTUM | LMNA 2587/4885CYP1A2 632/4885ALDH1A1 983/4885 |
| US-20140349990-A1 | Pyrazolopyrrolidine Derivatives and their Use in the Treatment of Disease | PKD1, PKD2, REN | LMNA 3686/4885CYP1A2 192/4885ALDH1A1 766/4885 |
| US-20170298080-A1 | AMINOSULFONYL COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | NOTUM, ALDH7A1, HADHB | LMNA 2474/4885CYP1A2 546/4885ALDH1A1 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.