Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 13/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 13/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468351 | 0.90 | RAB9A (0.45) | KMT2AITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL7461662 | 0.88 | ITGB3 (0.48) | ITGB3ITGA2BRAB9AALDH1A1LMNA | |
| SCHEMBL7468370 | 0.86 | KMT2A (0.49) | KMT2AITGB1ITGA4RAB9AALDH1A1 | |
| SCHEMBL7462016 | 0.86 | KMT2A (0.49) | KMT2AITGB1ITGA4RAB9AALDH1A1 | |
| SCHEMBL6438227 | 0.84 | ALDH1A1 (0.46) | KMT2AITGB3ITGA2BRAB9AALDH1A1 | |
| SCHEMBL7469934 | 0.84 | ITGB3 (0.49) | KMT2AITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL7466885 | 0.82 | CTNNB1 (0.47) | KMT2AITGB3ITGA2BRAB9AALDH1A1 | |
| SCHEMBL7472953 | 0.81 | ITGB1 (0.51) | ITGB1ITGA4ITGB3ITGA2BRAB9A | |
| SCHEMBL7463407 | 0.81 | ITGB3 (0.42) | KMT2AITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL7462096 | 0.81 | MMP2 (0.46) | ITGB3ITGA2BRAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |