Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475891 | 0.88 | ACHE (0.54) | ACHEBACE1MAPTLMNAALDH1A1 | |
| SCHEMBL7468815 | 0.87 | ACHE (0.51) | ACHEBACE1MAPTALDH1A1PDGFRB | |
| SCHEMBL7462225 | 0.85 | MAPT (0.55) | ACHEBACE1MAPTLMNAALDH1A1 | |
| SCHEMBL7464197 | 0.82 | SMN1; SMN2 (0.48) | ACHEBACE1MAPTLMNAGAA | |
| SCHEMBL7464038 | 0.80 | ACHE (0.55) | ACHEBACE1MAPTLMNAALDH1A1 | |
| SCHEMBL7475884 | 0.79 | ALDH1A1 (0.54) | ACHEBACE1MAPTLMNAALDH1A1 | |
| SCHEMBL7470741 | 0.77 | MAPT (0.42) | ACHEBACE1MAPTLMNAGAA | |
| SCHEMBL7476091 | 0.76 | ACHE (0.54) | ACHEBACE1MAPTLMNAALDH1A1 | |
| SCHEMBL7468805 | 0.76 | ALDH1A1 (0.54) | ACHEBACE1MAPTGAAALDH1A1 | |
| SCHEMBL7469219 | 0.76 | ACHE (0.41) | ACHEBACE1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |