Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468677 | 0.92 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1GAAKDM4EUSP2 | |
| SCHEMBL7469281 | 0.85 | PDGFRB (0.51) | SMN1; SMN2ALDH1A1GAAKDM4EUSP2 | |
| SCHEMBL7462225 | 0.83 | MAPT (0.55) | SMN1; SMN2ALDH1A1USP2HSD17B10L3MBTL1 | |
| SCHEMBL7471664 | 0.83 | CNR1 (0.55) | GPR174 | |
| SCHEMBL7462233 | 0.82 | ACHE (0.45) | SMN1; SMN2ALDH1A1GAAUSP2HSD17B10 | |
| SCHEMBL7464038 | 0.80 | ACHE (0.55) | SMN1; SMN2ALDH1A1L3MBTL1ACHEBACE1 | |
| SCHEMBL7470741 | 0.79 | MAPT (0.42) | SMN1; SMN2ALDH1A1GAAUSP2ACHE | |
| SCHEMBL7475891 | 0.77 | ACHE (0.54) | ALDH1A1KDM4EUSP2HSD17B10ACHE | |
| SCHEMBL7459033 | 0.77 | MAPT (0.46) | SMN1; SMN2ALDH1A1GAAMAPTLMNA | |
| SCHEMBL7476091 | 0.76 | ACHE (0.54) | SMN1; SMN2ALDH1A1KDM4EACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |