Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400517 | 0.77 | CYP2A6 (0.36) | BRS3PDPK1 | |
| SCHEMBL9440546 | 0.77 | NOTUM (0.45) | BRS3 | |
| Hydrochloric Acid SCHEMBL4739527 | 0.76 | NOTUM (0.44) | BRS3 | |
| SCHEMBL8470236 | 0.75 | PDPK1 (0.35) | PDPK1 | |
| SCHEMBL14895448 | 0.71 | ALDH1A1 (0.40) | BRS3PDPK1 | |
| SCHEMBL7402637 | 0.67 | ADH5 (0.47) | — | |
| SCHEMBL7321916 | 0.65 | KDM4E (0.46) | PDPK1 | |
| SCHEMBL16897456 | 0.64 | CXCR2 (0.36) | BRS3 | |
| SCHEMBL676377 | 0.62 | SMN1; SMN2 (0.60) | BRS3 | |
| SCHEMBL4582384 | 0.62 | NOTUM (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021181-A4 | CARBOXYLIC ACID INDOLE INHIBITORS OF CHEMOKINES | SMITHKLINE BEECHAM CORP (US) | 2002-06-26 | — | — | EP | disclosed |
| EP-1021181-A1 | CARBOXYLIC ACID INDOLE INHIBITORS OF CHEMOKINES | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5955492-A | Carboxylic acid indole inhibitors of chemokines | SMITHKLINE BEECHAM CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |
| WO-1997035572-A1 | CARBOXYLIC ACID INDOLE INHIBITORS OF CHEMOKINES | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-02 | — | — | WO | disclosed |