Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376072 | 0.78 | ACLY (0.35) | SYK | |
| SCHEMBL9272142 | 0.77 | MEN1 (0.42) | — | |
| SCHEMBL8230259 | 0.77 | NOTUM (0.51) | — | |
| SCHEMBL7463145 | 0.75 | BRS3 (0.35) | PDPK1 | |
| SCHEMBL2211763 | 0.74 | KDM4E (0.46) | — | |
| SCHEMBL19106909 | 0.73 | RXRA (0.41) | — | |
| SCHEMBL7372783 | 0.69 | P2RX7 (0.34) | — | |
| SCHEMBL7380141 | 0.69 | P2RX7 (0.34) | — | |
| SCHEMBL3059728 | 0.69 | GRM5 (0.38) | — | |
| SCHEMBL3147154 | 0.68 | CYP2A6 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11106341-A | — | — | None | — | — | JP | disclosed |
| JP-H11106341-A | PHARMACEUTICAL COMPOSITION CONTAINING 3-(5-TETRAZOLYL-BENZYL) AMINO-PIPERIDINE DERIVATIVE | GLAXO GROUP LTD | 1999-04-20 | — | — | JP | disclosed |
| EP-0720609-B1 | 3-(5-TETRAZOLYL-BENZYL)AMINO-PIPERIDINE DERIVATIVES AND ANTAGONISTS OF TACHYKININS | GLAXO GROUP LTD (GB) | 1998-11-11 | — | — | EP | disclosed |
| EP-0720609-A1 | 3-(5-TETRAZOLYL-BENZYL)AMINO-PIPERIDINE DERIVATIVES AND ANTAGONISTS OF TACHYKININS | GLAXO GROUP LIMITED (GB) | 1996-07-10 | — | — | EP | disclosed |