Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.43 |
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 5/20 | 0.40 |
| ▸ | AXL | P30530 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9452115 | 0.85 | GAA (0.37) | PDGFRACCNCCDK8SRCADRA1A | |
| SCHEMBL7460149 | 0.77 | RET (0.42) | RETPDGFRAKDRCCNCCDK8 | |
| SCHEMBL14285766 | 0.74 | RET (0.44) | RETPDGFRAKDRMETAXL | |
| Quinoxyfen SCHEMBL22257 | 0.74 | RET (0.42) | RETPDGFRAKDRMETAXL | |
| Quinoxyfen SCHEMBL28247243 | 0.74 | RET (0.42) | RETPDGFRAKDRMETAXL | |
| Quinoxyfen SCHEMBL7471425 | 0.73 | RET (0.41) | RETPDGFRAKDRMETAXL | |
| Quinoxyfen SCHEMBL1974400 | 0.73 | RET (0.41) | RETPDGFRAKDRMETAXL | |
| SCHEMBL27306670 | 0.72 | CCNC (0.43) | RETPDGFRAKDRCCNCCDK8 | |
| SCHEMBL7460943 | 0.71 | PDGFRA (0.56) | RETPDGFRAKDRMETAXL | |
| SCHEMBL7470310 | 0.70 | MAOA (0.38) | RETPDGFRAKDRCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |