Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467830 | 0.88 | MAPT (0.44) | CASP3MAPTMAPK1HTTALDH1A1 | |
| SCHEMBL7052909 | 0.87 | RAB9A (0.43) | MAPTHTTALDH1A1KDM4EKMT2A | |
| SCHEMBL7468705 | 0.84 | KDM4E (0.41) | MAPTMAPK1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7051580 | 0.81 | HPGD (0.50) | MAPTMAPK1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7470661 | 0.79 | OPRK1 (0.42) | CASP3MAPTMAPK1HTTALDH1A1 | |
| SCHEMBL7463266 | 0.79 | PRKD3 (0.47) | MAPTMAPK1HTTALDH1A1BAZ2B | |
| SCHEMBL382515 | 0.77 | HTT (0.51) | MAPTMAPK1HTTALDH1A1KDM4E | |
| SCHEMBL28044539 | 0.76 | MYC (0.42) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL17825662 | 0.70 | KMT2A (0.58) | MAPK1ALDH1A1BAZ2BBAZ2AKMT2A | |
| SCHEMBL17261711 | 0.70 | CYP4F2 (0.47) | MAPK1ALDH1A1BAZ2BBAZ2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |