Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 6/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656781 | 0.94 | CA9 (0.54) | CA9CA12CA1CA2CA13 | |
| SCHEMBL8660458 | 0.88 | PTGS2 (0.51) | CA9CA12CA1CA2CA13 | |
| SCHEMBL5189522 | 0.87 | CA9 (0.52) | CA9CA12CA1CA2CA13 | |
| SCHEMBL8657899 | 0.84 | CA9 (0.47) | CA9CA12CA1CA2CA13 | |
| SCHEMBL6356391 | 0.84 | CA9 (0.50) | CA9CA12CA1CA2CA13 | |
| SCHEMBL8657255 | 0.84 | CA9 (0.44) | CA9CA12CA1CA2CA13 | |
| SCHEMBL8661248 | 0.82 | PTGS2 (0.46) | CA9CA12CA1CA2MEN1 | |
| SCHEMBL6725775 | 0.82 | CA2 (0.75) | CA9CA12CA1CA2CA13 | |
| SCHEMBL8659436 | 0.81 | PTGS2 (0.51) | CA9CA12CA1CA2MEN1 | |
| SCHEMBL8663003 | 0.81 | PTGS2 (0.51) | CA9CA12CA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181269-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000073264-A1 | CELL PROLIFERATION INHIBITORS | ABBOTT LABORATORIES (US) | 2000-12-07 | — | — | WO | disclosed |