Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 10/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CALML3 | P27482 | 1/20 | 0.40 |
| ▸ | SDHA | P31040 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469138 | 0.90 | MAOA (0.48) | RAB9AMIFPDE3BPDE3AMAOB | |
| SCHEMBL7468825 | 0.80 | MAOB (0.59) | RAB9ANPC1MIFPDE3BPDE3A | |
| SCHEMBL14345346 | 0.80 | MAOB (0.59) | RAB9ANPC1MIFPDE3BPDE3A | |
| SCHEMBL7469864 | 0.80 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2MIF | |
| SCHEMBL7477204 | 0.79 | MIF (0.54) | RAB9ANPC1SMN1; SMN2MIF | |
| SCHEMBL7469769 | 0.78 | MIF (0.44) | RAB9ANPC1SMN1; SMN2MIFMAOB | |
| SCHEMBL7474027 | 0.78 | MAOA (0.48) | RAB9ANPC1SMN1; SMN2MIFMAOB | |
| SCHEMBL7478325 | 0.76 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2MIFMAOB | |
| SCHEMBL7467874 | 0.76 | MIF (0.42) | RAB9ANPC1SMN1; SMN2MIFMAOB | |
| SCHEMBL7471632 | 0.75 | MIF (0.47) | RAB9ANPC1SMN1; SMN2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054874-B1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-08-28 | — | — | EP | claimed |
| US-6069141-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 2000-05-30 | — | — | US | claimed |
| EP-1054874-B1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1054874-A1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-29 | — | — | EP | disclosed |
| US-6069141-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 2000-05-30 | — | — | US | disclosed |
| WO-1999041244-A1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-19 | — | — | WO | disclosed |