Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 8/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pivalate SCHEMBL27380361 | 0.81 | TSHR (0.55) | PPARAPPARGTSHRMEN1KMT2A | |
| Chlorobenzene SCHEMBL11539353 | 0.79 | TSHR (0.52) | RIPK1PPARAPPARGTSHRMEN1 | |
| Dimebutic Acid SCHEMBL47533 | 0.78 | — | — | |
| Chlorobenzene SCHEMBL11001235 | 0.77 | TSHR (0.50) | PPARAPPARGTSHRMEN1KMT2A | |
| Chlorobenzene SCHEMBL6906848 | 0.76 | TSHR (0.55) | TSHRKMT2ACYP1A2MAPTCYP2C19 | |
| Chlorobenzene SCHEMBL27460518 | 0.76 | TSHR (0.55) | TSHRKMT2ACYP1A2MAPTCYP2C19 | |
| Dimebutic Acid SCHEMBL25275531 | 0.75 | — | — | |
| Dimebutic Acid SCHEMBL1962006 | 0.75 | — | — | |
| Dimebutic Acid SCHEMBL20139427 | 0.75 | — | — | |
| Dimebutic Acid SCHEMBL1055427 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724586-B1 | PROCESS FOR PREPARING N-(2,6-DICHLORO-3-METHYLPHENYL)-5-7-DIHALO[1,2,4]TRIAZOLO[1,5A]PYRIMIDINE-2-SULFONAMIDE BY CYCLIZATION AND HALO-DEHYDROXYLATION | DOW AGROSCIENCES LLC (US) | 2002-01-23 | — | — | EP | claimed |