Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684034 | 1.00 | ICAM1 (0.38) | ICAM1SELEALOX5NPC1RAB9A | |
| SCHEMBL6948291 | 0.86 | HCAR2 (0.41) | ICAM1SELENPC1RAB9ATSHR | |
| SCHEMBL6948288 | 0.86 | HCAR2 (0.41) | ICAM1SELENPC1RAB9ATSHR | |
| SCHEMBL18905887 | 0.76 | MAPT (0.54) | LMNAALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL7464335 | 0.72 | MAPT (0.38) | ICAM1SELENPC1RAB9ATSHR | |
| SCHEMBL5496057 | 0.71 | KDM4E (0.41) | ICAM1SELEALOX5NPC1RAB9A | |
| SCHEMBL5989665 | 0.70 | — | — | |
| SCHEMBL7456040 | 0.68 | ALDH1A1 (0.60) | PKMLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7463649 | 0.68 | ICAM1 (0.39) | ICAM1SELEALOX5NPC1RAB9A | |
| SCHEMBL921135 | 0.67 | CA12 (0.41) | ICAM1SELEALOX5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235826-A1 | QUINUCLIDINE ACRYLAMIDES | AstraZeneca AB (SE) | 2002-09-04 | — | — | EP | claimed |
| WO-2001029034-A1 | QUINUCLIDINE ACRYLAMIDES | ASTRAZENECA AB (SE) | 2001-04-26 | — | — | WO | claimed |