Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.69 |
| ▸ | CA1 | P00915 | 5/20 | 0.68 |
| ▸ | CA2 | P00918 | 5/20 | 0.68 |
| ▸ | CA7 | P43166 | 5/20 | 0.68 |
| ▸ | CA9 | Q16790 | 3/20 | 0.68 |
| ▸ | CA12 | O43570 | 3/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.67 |
| ▸ | DRD2 | P14416 | 4/20 | 0.60 |
| ▸ | DRD3 | P35462 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | HRH1 | P35367 | 2/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31680794 | 0.82 | HRH3 (0.78) | HRH3CA1CA2CA7CA9 | |
| SCHEMBL7466649 | 0.82 | HRH3 (1.00) | HRH3CA1CA2CA7CA9 | |
| SCHEMBL7470346 | 0.81 | CA12 (1.00) | HRH3CA1CA2CA7CA9 | |
| SCHEMBL11241598 | 0.80 | DRD2 (0.68) | HRH3DRD2DRD3HTR1AHTR2A | |
| SCHEMBL8701504 | 0.80 | DRD2 (0.58) | HRH3CA1CA2CA9CA12 | |
| SCHEMBL31217459 | 0.79 | HRH3 (0.60) | HRH3CA1CA2CA7CA9 | |
| SCHEMBL11240961 | 0.79 | LTA4H (0.74) | HRH3KCNH2DRD2DRD3HTR1A | |
| SCHEMBL11879949 | 0.77 | HRH1 (0.73) | HRH3DRD2DRD3HTR1AHTR2A | |
| SCHEMBL32689495 | 0.76 | HRH3 (0.79) | HRH3CA1CA2CA7CA9 | |
| SCHEMBL11249924 | 0.74 | DRD2 (0.60) | HRH3DRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |