Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.58 |
| ▸ | DRD3 | P35462 | 4/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | DRD5 | P21918 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 6/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705478 | 0.85 | TDP1 (0.57) | DRD2DRD3DRD1DRD5HRH3 | |
| SCHEMBL1957719 | 0.84 | TSHR (0.58) | DRD2DRD3DRD1DRD5HRH3 | |
| SCHEMBL7464010 | 0.80 | HRH3 (0.69) | DRD2DRD3HTR1AHRH3SIGMAR1 | |
| SCHEMBL32689498 | 0.79 | MEN1 (0.52) | DRD3HTR1AHRH3CYP2D6POLB | |
| SCHEMBL10794504 | 0.77 | DRD2 (0.66) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL32689500 | 0.75 | KDM4E (0.50) | HRH3SIGMAR1HRH1CYP2D6KCNH2 | |
| SCHEMBL10863756 | 0.75 | SIGMAR1 (0.49) | DRD2HTR1ASIGMAR1HTR2AKCNH2 | |
| SCHEMBL8692475 | 0.74 | HTR1A (0.75) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL10860089 | 0.73 | KCNH2 (0.62) | DRD2DRD3DRD1DRD5HTR1A | |
| SCHEMBL7007212 | 0.71 | POLB (0.56) | DRD1DRD5CYP2D6POLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |