Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | IL6 | P05231 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6949653 | 0.93 | F11 (0.44) | KDM4ECHRM4MAPK1HRH3IL6 | |
| SCHEMBL6949028 | 0.88 | KDM4E (0.46) | KDM4EMAPK1HRH3IL6TLR7 | |
| SCHEMBL12965907 | 0.85 | KDM4E (0.45) | KDM4EHRH3IL6TLR7L3MBTL1 | |
| SCHEMBL9733579 | 0.83 | HRH3 (0.57) | KDM4EMAPK1HRH3NPC1RAB9A | |
| SCHEMBL22465802 | 0.83 | KDM4E (0.44) | KDM4ECHRM4MAPK1HRH3NPC1 | |
| SCHEMBL1857662 | 0.82 | HRH3 (0.59) | KDM4EMAPK1HRH3NPC1RAB9A | |
| SCHEMBL12965883 | 0.81 | KDM4E (0.64) | KDM4ECHRM4MAPK1KMT2AKDM1A | |
| SCHEMBL9202121 | 0.81 | CHKA (0.55) | KDM4EMAPK1HRH3NPC1RAB9A | |
| SCHEMBL7078749 | 0.81 | CKS1B (0.48) | KDM4ECHRM4KDM1AHDAC6JAK2 | |
| SCHEMBL13059656 | 0.81 | RAB9A (0.60) | MAPK1HRH3NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-B1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI SYNTHELABO (FR) | 2002-08-14 | — | — | EP | disclosed |
| EP-1087961-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065895-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 1999-12-23 | — | — | WO | disclosed |