Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310518 | 1.00 | ACHE (0.56) | ACHEBCHECHRM4DRD2HTR2A | |
| SCHEMBL9348980 | 0.87 | SIGMAR1 (0.60) | ACHEBCHEDRD2HTR2AHTR2C | |
| SCHEMBL7307530 | 0.87 | SIGMAR1 (0.60) | ACHEBCHEDRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7307590 | 0.86 | DRD2 (0.59) | ACHEBCHEDRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7475554 | 0.85 | DRD2 (0.58) | ACHEBCHEDRD2HTR2AHTR2C | |
| SCHEMBL14601873 | 0.82 | DRD2 (0.66) | ACHEBCHECHRM4DRD2DRD4 | |
| SCHEMBL13436307 | 0.81 | CHRM4 (0.65) | ACHEBCHECHRM4 | |
| SCHEMBL7417275 | 0.80 | HDAC3 (0.53) | ACHECHRM4 | |
| SCHEMBL7316439 | 0.80 | HDAC3 (0.53) | ACHECHRM4 | |
| SCHEMBL18825768 | 0.79 | CHRM4 (0.67) | ACHEBCHECHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009094-A1 | ETHER DERIVATIVES OF ALKYL PIPERIDINES AND PYRROLIDINES AS ANTIPSYCHOTIC AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |