Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.60 |
| ▸ | DRD2 | P14416 | 4/20 | 0.60 |
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | HTR2C | P28335 | 4/20 | 0.60 |
| ▸ | HTR2B | P41595 | 4/20 | 0.60 |
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 4/20 | 0.58 |
| ▸ | ACHE | P22303 | 4/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348980 | 1.00 | SIGMAR1 (0.60) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL7307590 | 0.99 | DRD2 (0.59) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL7475554 | 0.97 | DRD2 (0.58) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9349521 | 0.87 | CCR3 (0.55) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL7312328 | 0.87 | CCR3 (0.55) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL7464204 | 0.87 | ACHE (0.56) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL7310518 | 0.87 | ACHE (0.56) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9350010 | 0.85 | CHRNB2 (0.57) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL8549859 | 0.81 | DRD2 (0.85) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL8555532 | 0.80 | DRD2 (0.83) | SIGMAR1DRD2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5317024-A | Administering to mammals | DUPONT MERCK PHARMACEUTICAL CO. (US) | 1994-05-31 | — | — | US | claimed |
| US-5252586-A | Ether derivatives of alkyl piperidines and pyrrolidines as antipsychotic agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-10-12 | — | — | US | claimed |
| WO-1993009094-A1 | ETHER DERIVATIVES OF ALKYL PIPERIDINES AND PYRROLIDINES AS ANTIPSYCHOTIC AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-05-13 | — | — | WO | claimed |
| US-5317024-A | Administering to mammals | DUPONT MERCK PHARMACEUTICAL CO. (US) | 1994-05-31 | — | — | US | disclosed |
| US-5252586-A | Ether derivatives of alkyl piperidines and pyrrolidines as antipsychotic agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-10-12 | — | — | US | disclosed |