SCHEMBL7464302

SCHEMBL7464302

CC(=O)OC(CF)c1ncccc1S(=O)(=O)NC(=O)NC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRS3 P32247 13/20 0.44
TBXA2R P21731 4/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9217880 0.87 USP30 (0.35)
SCHEMBL7458077 0.86 ALDH1A1 (0.34) TSHR
SCHEMBL7458447 0.81 GAA (0.50)
SCHEMBL9266513 0.79 CA1 (0.38) TSHR
SCHEMBL7459534 0.76 BRS3 (0.37) BRS3TBXA2RTSHR
SCHEMBL7464310 0.72
SCHEMBL8106979 0.69 ALOX5AP (0.35)
SCHEMBL7458440 0.69 SMN1; SMN2 (0.36) TSHR
SCHEMBL7806538 0.69 USP30 (0.34)
SCHEMBL7459569 0.68 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639190-B1 PYRIDINE SULFONYL UREA DERIVATIVES LG CHEM INVESTMENT LTD (KR) 2002-01-09 EP disclosed