Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746436 | 0.80 | CSNK1A1 (0.38) | PARP1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL17295879 | 0.74 | BCAT2 (0.46) | PARP1LMNAHTTPARP2KEAP1 | |
| SCHEMBL16463453 | 0.71 | PARP1 (0.40) | PARP1LMNAHTTPARP2KDM4E | |
| SCHEMBL986588 | 0.71 | CSNK1A1 (0.46) | PARP1PARP2KDM4EALDH1A1HPGD | |
| SCHEMBL334956 | 0.70 | KMT2A (0.47) | LMNAHTTKDM4EALDH1A1HPGD | |
| SCHEMBL29503449 | 0.70 | CSNK1A1 (0.58) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16463699 | 0.70 | KDM4E (0.40) | PARP1LMNAHTTPARP2KDM4E | |
| SCHEMBL461600 | 0.70 | PARP1 (0.41) | PARP1LMNAHTTPARP2KDM4E | |
| SCHEMBL144959 | 0.70 | PARP1 (0.44) | PARP1LMNAHTTPARP2KDM4E | |
| SCHEMBL3352032 | 0.70 | PARP1 (0.41) | PARP1LMNAHTTPARP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138356-B2 | Chemical inhibitors of inhibitors of differentiation | Angiogeney, Inc. (US) | 2012-03-20 | — | — | US | disclosed |