Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 11/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746434 | 0.80 | PARP1 (0.37) | CSNK1A1TYRO3DYRK1BPARP1KDM4E | |
| SCHEMBL29503449 | 0.79 | CSNK1A1 (0.58) | CSNK1A1TYRO3DYRK1BPARP1NUDT1 | |
| SCHEMBL2964481 | 0.75 | PARP1 (0.45) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5476512 | 0.74 | BCAT2 (0.59) | PARP1PPARGALDH1A1KEAP1NFE2L2 | |
| SCHEMBL370726 | 0.72 | MYC (0.45) | PARP1PPARGKDM4EALDH1A1HPGD | |
| SCHEMBL986590 | 0.72 | CSNK1A1 (0.47) | CSNK1A1TYRO3DYRK1BPARP1NUDT1 | |
| SCHEMBL5478290 | 0.71 | PARP1 (0.45) | PARP1PPARGKDM4EALDH1A1KEAP1 | |
| SCHEMBL5482646 | 0.71 | PPARG (0.45) | PARP1PPARGKDM4EALDH1A1HPGD | |
| SCHEMBL5481197 | 0.71 | PARP1 (0.40) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16463457 | 0.71 | PARP1 (0.40) | PARP1PPARGKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138356-B2 | Chemical inhibitors of inhibitors of differentiation | Angiogeney, Inc. (US) | 2012-03-20 | — | — | US | disclosed |