Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PTGFR | P43088 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459141 | 1.00 | NPC1 (0.41) | NPC1RAB9APTGFRANPEPITGB1 | |
| SCHEMBL7464096 | 0.85 | NPC1 (0.43) | NPC1RAB9APTGFRANPEPITGB1 | |
| SCHEMBL7462350 | 0.85 | NPC1 (0.43) | NPC1RAB9APTGFRANPEPITGB1 | |
| SCHEMBL7213313 | 0.84 | ITGB1 (0.52) | NPC1RAB9AITGB1ITGA4KMT2A | |
| SCHEMBL7219807 | 0.83 | ITGB1 (0.54) | NPC1RAB9AITGB1ITGA4 | |
| SCHEMBL7467442 | 0.77 | KMT2A (0.49) | NPC1ITGB1ITGA4KMT2AALDH1A1 | |
| SCHEMBL7462016 | 0.76 | KMT2A (0.49) | RAB9AITGB1ITGA4KMT2AALDH1A1 | |
| SCHEMBL7468370 | 0.76 | KMT2A (0.49) | RAB9AITGB1ITGA4KMT2AALDH1A1 | |
| SCHEMBL7468356 | 0.75 | KMT2A (0.45) | RAB9AITGB1ITGA4KMT2AALDH1A1 | |
| SCHEMBL7467419 | 0.74 | NPC1 (0.49) | NPC1RAB9AITGB1ITGA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |