Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382963 | 0.89 | SMYD3 (0.43) | CNR1CNR2KDM4EHTTHDAC3 | |
| SCHEMBL7466337 | 0.89 | CNR1 (0.43) | CNR1CNR2KDM4EHTTHDAC3 | |
| SCHEMBL6496334 | 0.88 | CNR1 (0.43) | CNR1CNR2KDM4EHTTHDAC3 | |
| SCHEMBL6503936 | 0.85 | CNR1 (0.41) | CNR1CNR2KDM4EHTTHDAC3 | |
| SCHEMBL382677 | 0.84 | ITGB3 (0.43) | KDM4EHTTDRD2DRD3EPHX2 | |
| SCHEMBL7467073 | 0.84 | VCP (0.41) | CNR1CNR2KDM4EHTTHDAC3 | |
| SCHEMBL7457979 | 0.84 | SFRP1 (0.42) | CNR1CNR2KDM4EHTTDRD2 | |
| SCHEMBL382100 | 0.83 | ITGB3 (0.46) | DRD2DRD3DRD4 | |
| SCHEMBL7468782 | 0.81 | DRD4 (0.42) | CNR1CNR2HTTDRD2DRD3 | |
| SCHEMBL7539445 | 0.81 | CNR1 (0.44) | CNR1CNR2KDM4EHTTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | claimed |
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | disclosed |