Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | VCP | P55072 | 2/20 | 0.38 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.37 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.37 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496334 | 0.90 | CNR1 (0.43) | CNR1CNR2HDAC3HDAC1KDM4E | |
| SCHEMBL6503936 | 0.89 | CNR1 (0.41) | CNR1CNR2HDAC3HDAC1KDM4E | |
| SCHEMBL7464413 | 0.89 | CNR1 (0.45) | CNR1CNR2HDAC3HDAC1KDM4E | |
| SCHEMBL7467073 | 0.86 | VCP (0.41) | CNR1CNR2HDAC3HDAC1KDM4E | |
| SCHEMBL7457979 | 0.84 | SFRP1 (0.42) | CNR1CNR2KDM4EHTTDRD4 | |
| SCHEMBL7468782 | 0.82 | DRD4 (0.42) | CNR1CNR2HTTDRD4DRD2 | |
| SCHEMBL381765 | 0.81 | ALDH1A1 (0.46) | CNR1CNR2HDAC1KDM4EHTT | |
| SCHEMBL6499244 | 0.79 | CNR1 (0.38) | CNR1CNR2HDAC3HDAC1KDM4E | |
| SCHEMBL382963 | 0.79 | SMYD3 (0.43) | CNR1CNR2HDAC3HDAC1KDM4E | |
| SCHEMBL6499974 | 0.78 | ITGB3 (0.43) | CNR1CNR2HDAC1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | claimed |
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | disclosed |