Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | KYNU | Q16719 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423070 | 0.89 | USP30 (0.49) | CA1CA2F10PRSS1RAB9A | |
| SCHEMBL7415012 | 0.88 | CYP26A1 (0.46) | CA1CA2F10RAB9AGAA | |
| SCHEMBL3540630 | 0.78 | RAB9A (0.54) | RAB9AMAPTGAACYP26A1MEN1 | |
| SCHEMBL3534617 | 0.77 | MEN1 (0.54) | CA1CA2RAB9AMAPTMEN1 | |
| SCHEMBL7417679 | 0.76 | CASP1 (0.51) | CA1CA2F10RAB9AGAA | |
| SCHEMBL7418216 | 0.75 | F10 (0.56) | F10RAB9AMAPTGAAMEN1 | |
| SCHEMBL7417684 | 0.74 | CASP1 (0.44) | CA1CA2F10PRSS1RAB9A | |
| Trifluoroacetic Acid SCHEMBL6165833 | 0.74 | F10 (0.58) | F10PRSS1 | |
| SCHEMBL16667936 | 0.74 | GAA (0.58) | RAB9AGAAALDH1A1MMP9LMNA | |
| Trifluoroacetic Acid SCHEMBL6165839 | 0.73 | ALDH1A1 (0.44) | CA1CA2F10PRSS1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235807-A1 | B-AMINO ACID-, ASPARTIC ACID- AND DIAMINOPROPIONIC-BASED INHIBITORS OF FACTOR XA | Millennium Pharmaceuticals, Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038309-A1 | β-AMINO ACID-, ASPARTIC ACID- AND DIAMINOPROPIONIC-BASED INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-05-31 | — | — | WO | disclosed |