Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.68 |
| ▸ | BCR | P11274 | 13/20 | 0.68 |
| ▸ | PRKCA | P17252 | 11/20 | 0.68 |
| ▸ | SRC | P12931 | 8/20 | 0.68 |
| ▸ | PRKCD | Q05655 | 8/20 | 0.68 |
| ▸ | EGFR | P00533 | 5/20 | 0.68 |
| ▸ | AGER | Q15109 | 1/20 | 0.62 |
| ▸ | PRKACA | P17612 | 1/20 | 0.57 |
| ▸ | PRKACG | P22612 | 1/20 | 0.57 |
| ▸ | PRKACB | P22694 | 1/20 | 0.57 |
| ▸ | ABL2 | P42684 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | PRKCG | P05129 | 1/20 | 0.52 |
| ▸ | PRKCB | P05771 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466120 | 0.90 | AGER (0.67) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7474933 | 0.89 | ABL1 (0.68) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7464949 | 0.82 | AGER (0.59) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7474612 | 0.82 | PIK3CG (0.76) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL13924608 | 0.81 | SYK (0.66) | SRCAGERZAP70 | |
| SCHEMBL6265857 | 0.81 | ABL1 (1.00) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7052995 | 0.81 | AGER (0.60) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7052367 | 0.81 | AGER (0.66) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7472256 | 0.78 | IKBKB (0.68) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7528647 | 0.77 | ABL1 (0.72) | ABL1BCRPRKCASRCPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-0636025-A4 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES. | — | 1995-02-22 | — | — | EP | disclosed |
| EP-0636025-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993019750-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |