Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP8 | P40818 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464351 | 0.95 | ACHE (0.51) | ACHETP53NTRK1GUSBKDM4E | |
| SCHEMBL7464639 | 0.86 | TP53 (0.60) | ACHETP53KDM4EL3MBTL1ADORA2A | |
| SCHEMBL7458826 | 0.86 | TP53 (0.60) | ACHETP53KDM4EL3MBTL1ADORA2A | |
| SCHEMBL7822017 | 0.81 | NTRK1 (0.51) | ACHENTRK1GUSBKDM4EL3MBTL1 | |
| SCHEMBL3736581 | 0.81 | NTRK1 (0.51) | ACHENTRK1GUSBKDM4EL3MBTL1 | |
| SCHEMBL7811355 | 0.79 | NTRK1 (0.50) | ACHETP53NTRK1GUSBKDM4E | |
| SCHEMBL7456185 | 0.77 | TP53 (0.44) | ACHETP53NTRK1GUSBUSP8 | |
| Hydrochloric Acid SCHEMBL7461388 | 0.76 | TP53 (0.43) | ACHETP53NTRK1GUSBUSP8 | |
| SCHEMBL7456175 | 0.76 | TERT (0.48) | ADORA2AADORA1POLBKMT2A | |
| SCHEMBL3733796 | 0.76 | GUSB (0.52) | ACHENTRK1GUSBKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785191-B1 | FUSED INDAN DERIVATIVES AND SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2002-10-23 | — | — | EP | disclosed |
| US-5763453-A | ANTITUMOR AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0785191-A1 | FUSED INDAN DERIVATIVES AND SALTS THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |