Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468263 | 0.92 | CNR1 (0.38) | CYP1A2CYP2C19MAPTCYP2C9HTT | |
| SCHEMBL7462111 | 0.90 | CYP1A2 (0.40) | CYP1A2CYP2C19MAPTCYP2C9HTT | |
| SCHEMBL7458931 | 0.82 | NSD2 (0.56) | MAPTHTTNSD2KMT2AMEN1 | |
| SCHEMBL7470513 | 0.82 | CNR1 (0.53) | MAPTHTTKMT2ACNR1CNR2 | |
| SCHEMBL7463135 | 0.82 | CNR1 (0.53) | MAPTCNR1CNR2ALDH1A1LMNA | |
| SCHEMBL7463150 | 0.81 | CYP1A2 (0.41) | CYP1A2CYP2C19MAPTCYP2C9HTT | |
| SCHEMBL7464723 | 0.80 | PDGFRB (0.51) | MAPT | |
| SCHEMBL7467225 | 0.80 | PAK1 (0.46) | MAPTHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7469276 | 0.77 | MAPT (0.41) | CYP1A2CYP2C19MAPTCYP2C9HTT | |
| SCHEMBL7471664 | 0.76 | CNR1 (0.55) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |