Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463150 | 0.90 | CYP1A2 (0.41) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL7463135 | 0.82 | CNR1 (0.53) | MAPTALDH1A1CNR1CNR2LMNA | |
| SCHEMBL7469270 | 0.81 | KMT2A (0.49) | MAPTCYP1A2CYP3A4CLK4ALDH1A1 | |
| SCHEMBL7464723 | 0.80 | PDGFRB (0.51) | MAPT | |
| SCHEMBL7458931 | 0.79 | NSD2 (0.56) | MAPTHTTALDH1A1CNR1CNR2 | |
| SCHEMBL7470513 | 0.78 | CNR1 (0.53) | MAPTHTTALDH1A1CNR1CNR2 | |
| SCHEMBL7467225 | 0.78 | PAK1 (0.46) | MAPTHTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7468264 | 0.78 | PAK1 (0.48) | — | |
| SCHEMBL7466535 | 0.77 | CYP1A2 (0.38) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL7475891 | 0.77 | ACHE (0.54) | MAPTCYP1A2CYP2C19HTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |