Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457512 | 0.95 | MCHR1 (0.56) | MCHR1CCR3 | |
| SCHEMBL7461321 | 0.90 | MCHR1 (0.51) | MCHR1HTR1ADRD2HTR2AHTR2C | |
| SCHEMBL7464781 | 0.84 | MCHR1 (0.73) | MCHR1DRD2HTR7CCR3KCNA3 | |
| SCHEMBL7459547 | 0.84 | MCHR1 (0.65) | MCHR1HTR1ADRD2DRD3ADRA1A | |
| SCHEMBL7464717 | 0.83 | MCHR1 (0.64) | MCHR1DRD3HTR7CCR3ADRA1D | |
| SCHEMBL7457730 | 0.82 | MCHR1 (0.48) | MCHR1HDAC1HDAC3CCR3 | |
| SCHEMBL7462229 | 0.82 | MCHR1 (0.62) | MCHR1HTR1ADRD2HTR2AHTR2C | |
| SCHEMBL7458838 | 0.82 | MCHR1 (0.65) | MCHR1HTR1ADRD2HTR2AHTR2C | |
| SCHEMBL7465382 | 0.82 | MCHR1 (0.62) | MCHR1HTR1ADRD2HTR2AHTR2C | |
| SCHEMBL7470119 | 0.81 | MCHR1 (0.68) | MCHR1DRD2DRD3HTR7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |