Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 13/20 | 0.47 |
| ▸ | DRD3 | P35462 | 10/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | PLD2 | O14939 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464781 | 0.84 | MCHR1 (0.73) | MCHR1DRD2HTR7 | |
| SCHEMBL7459547 | 0.84 | MCHR1 (0.65) | MCHR1SLC6A4SLC6A2DRD2DRD3 | |
| SCHEMBL7464717 | 0.83 | MCHR1 (0.64) | MCHR1DRD3HTR7ADRA1DADRA1A | |
| SCHEMBL7462229 | 0.82 | MCHR1 (0.62) | MCHR1SLC6A4SLC6A2DRD2DRD3 | |
| SCHEMBL7458838 | 0.82 | MCHR1 (0.65) | MCHR1SLC6A4SLC6A2DRD2DRD3 | |
| SCHEMBL7464932 | 0.82 | MCHR1 (0.62) | MCHR1DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7470119 | 0.81 | MCHR1 (0.68) | MCHR1SLC6A4SLC6A2DRD2DRD3 | |
| SCHEMBL7465464 | 0.81 | MCHR1 (0.63) | MCHR1DRD3HTR7DRD4ADRA1D | |
| SCHEMBL7460278 | 0.80 | MCHR1 (0.71) | MCHR1HTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL7463521 | 0.80 | MCHR1 (0.66) | MCHR1HTR7PLD2PLD1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |