Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | MAT2A | P31153 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462723 | 0.83 | HTR6 (0.49) | SRCHTR6DRD2 | |
| SCHEMBL4456875 | 0.81 | MAT2A (0.42) | CMA1MAT2AHTR6 | |
| SCHEMBL7464965 | 0.78 | CMA1 (0.85) | CMA1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL8707152 | 0.75 | MAT2A (0.43) | CMA1MAT2AMEN1LMNAKMT2A | |
| SCHEMBL8706870 | 0.75 | MAT2A (0.36) | CMA1MAT2ALMNAPSEN1PSEN2 | |
| SCHEMBL22103051 | 0.74 | MAT2A (0.72) | MAT2AMEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL24808382 | 0.70 | MAT2A (0.49) | MAT2AMEN1LMNAKMT2A | |
| SCHEMBL4063446 | 0.70 | CHRM1 (0.50) | CMA1SRCMEN1LMNAKMT2A | |
| SCHEMBL16487128 | 0.70 | SRC (0.45) | CMA1SRCPPARGPPARDPPARA | |
| SCHEMBL22093538 | 0.69 | MAT2A (0.55) | MAT2AMEN1LMNAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |