Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472700 | 0.85 | CMA1 (0.55) | GAACMA1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL7467945 | 0.79 | AKR1B1 (0.39) | GAAHPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8705102 | 0.78 | GAA (0.38) | GAAL3MBTL1KDM4EHPGDHSD17B10 | |
| SCHEMBL8701280 | 0.78 | TDP1 (0.40) | MAT2ACMA1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL7464976 | 0.75 | CMA1 (0.53) | MAT2ACMA1L3MBTL1MEN1KMT2A | |
| SCHEMBL7460868 | 0.75 | GAA (0.36) | GAAL3MBTL1HPGDTDP1MAPT | |
| SCHEMBL3786281 | 0.75 | CMA1 (0.64) | CMA1L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL3786870 | 0.73 | CMA1 (0.53) | GAACMA1L3MBTL1KDM4EHPGD | |
| SCHEMBL7472835 | 0.73 | SMN1; SMN2 (0.43) | CMA1L3MBTL1KDM4EHPGDMAPT | |
| SCHEMBL4456875 | 0.73 | MAT2A (0.42) | MAT2ACMA1ALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |