SCHEMBL7464982

SCHEMBL7464982

CCOc1ccccc1Oc1ccnc2c(Cl)cccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
NR4A2 P43354 1/20 0.45
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 2/20 0.45
HTT P42858 1/20 0.43
HSD17B10 Q99714 1/20 0.43
POLB P06746 3/20 0.43
LMNA P02545 1/20 0.42
APP P05067 1/20 0.41
CBFB Q13951 1/20 0.40
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
MAPT P10636 1/20 0.39
ATM Q13315 1/20 0.39
THRB P10828 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13763605 0.88 NR4A2 (0.53) L3MBTL1NR4A2ALDH1A1SMN1; SMN2KDM4E
SCHEMBL7461220 0.86 NR4A2 (0.47) L3MBTL1NR4A2ALDH1A1SMN1; SMN2KDM4E
SCHEMBL7466638 0.85 NR4A2 (0.53) NR4A2ALDH1A1SMN1; SMN2KDM4EHTT
SCHEMBL7531657 0.85 NR4A2 (0.59) L3MBTL1NR4A2ALDH1A1SMN1; SMN2KDM4E
SCHEMBL7466203 0.85 NR4A2 (0.44) L3MBTL1NR4A2ALDH1A1SMN1; SMN2KDM4E
SCHEMBL7467027 0.83 NR4A2 (0.45) L3MBTL1NR4A2ALDH1A1SMN1; SMN2KDM4E
SCHEMBL7464651 0.83 NR4A2 (0.47) NR4A2ALDH1A1SMN1; SMN2KDM4EHTT
SCHEMBL7464015 0.80 NR4A2 (0.47) NR4A2ALDH1A1SMN1; SMN2KDM4EHTT
SCHEMBL7471877 0.80 NR4A2 (0.47) NR4A2ALDH1A1SMN1; SMN2KDM4EHTT
SCHEMBL7465295 0.80 KDM4E (0.58) NR4A2ALDH1A1SMN1; SMN2KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326330-B1 Quinoline fungicides DOW AGROSCIENCES LLC (US) 2002-07-24 EP claimed
US-5145843-A For plants DOWELANCO (US) 1992-09-08 US claimed
EP-0326330-B1 Quinoline fungicides DOW AGROSCIENCES LLC (US) 2002-07-24 EP disclosed