Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458487 | 0.88 | NR4A2 (0.41) | NR4A2SMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL7466638 | 0.88 | NR4A2 (0.53) | NR4A2SMN1; SMN2LMNANR1H2NR1H3 | |
| SCHEMBL7531657 | 0.87 | NR4A2 (0.59) | NR4A2SMN1; SMN2LMNANR1H2NR1H3 | |
| SCHEMBL7465640 | 0.85 | NR4A2 (0.42) | NR4A2SMN1; SMN2LMNANR1H2NR1H3 | |
| SCHEMBL7462376 | 0.85 | ALDH1A1 (0.49) | NR4A2SMN1; SMN2LMNANR1H2NR1H3 | |
| SCHEMBL7461220 | 0.82 | NR4A2 (0.47) | NR4A2SMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL7464651 | 0.82 | NR4A2 (0.47) | NR4A2SMN1; SMN2NR1H2NR1H3KDM4E | |
| SCHEMBL7464015 | 0.82 | NR4A2 (0.47) | NR4A2SMN1; SMN2LMNANR1H2NR1H3 | |
| SCHEMBL7465295 | 0.82 | KDM4E (0.58) | NR4A2SMN1; SMN2NR1H2NR1H3KDM4E | |
| SCHEMBL7464982 | 0.80 | L3MBTL1 (0.46) | NR4A2SMN1; SMN2LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |
| US-5240940-A | Synergistic nmixture | DOWELANCO (US) | 1993-08-31 | — | — | US | disclosed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | disclosed |
| EP-0326330-A2 | Quinoline, quinazoline, and cinnoline fungicides | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |