Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.50 |
| ▸ | USP10 | Q14694 | 1/20 | 0.48 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.48 |
| ▸ | USP13 | Q92995 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.44 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473166 | 0.91 | HTR6 (0.55) | EGFRERBB2USP10PIK3C3USP13 | |
| SCHEMBL7475282 | 0.88 | USP10 (0.48) | EGFRERBB2USP10PIK3C3USP13 | |
| SCHEMBL7463091 | 0.87 | USP10 (0.50) | EGFRERBB2USP10PIK3C3USP13 | |
| SCHEMBL7466238 | 0.86 | USP10 (0.48) | EGFRERBB2USP10PIK3C3USP13 | |
| SCHEMBL7466273 | 0.85 | PDE5A (0.57) | ALDH1A1KMT2A | |
| SCHEMBL7473662 | 0.84 | USP10 (0.47) | EGFRERBB2USP10PIK3C3USP13 | |
| SCHEMBL7470182 | 0.82 | HTT (0.50) | MAPTLMNAALDH1A1HTTWDR5 | |
| SCHEMBL7471194 | 0.82 | MAPK1 (0.48) | EGFRMAPTLMNAALDH1A1HTT | |
| SCHEMBL7464890 | 0.82 | HRH4 (0.48) | MAPTLMNAALDH1A1HTTHTR6 | |
| SCHEMBL7469571 | 0.81 | EGFR (0.56) | EGFRMAPTLMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |