Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP10 | Q14694 | 1/20 | 0.48 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.48 |
| ▸ | USP13 | Q92995 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 7/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475664 | 0.92 | EGFR (0.55) | EGFRHTTALDH1A1MAPTTDP1 | |
| SCHEMBL7470693 | 0.91 | HTT (0.45) | USP10PIK3C3USP13EGFRHTT | |
| SCHEMBL7473166 | 0.89 | HTR6 (0.55) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL7465353 | 0.88 | EGFR (0.50) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL7463091 | 0.87 | USP10 (0.50) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL7466238 | 0.86 | USP10 (0.48) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL7468674 | 0.85 | PDE5A (0.57) | ALDH1A1 | |
| SCHEMBL7473662 | 0.84 | USP10 (0.47) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL7458966 | 0.83 | MAPK1 (0.47) | EGFRHTTHTR6CNR1CNR2 | |
| SCHEMBL7470593 | 0.82 | HTT (0.50) | HTTCNR1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |